Pain Management During Labor and Delivery in a Patient with Possible Local Anesthetic Resistance: A Case Report

Background: Local anesthetic resistance is a clinical entity characterized by inadequate analgesia despite technically well-performed procedures. The exact etiology and pathogenesis of this condition are not yet fully understood. Case Presentation: A 36-year-old Caucasian female presented to labor delivery for induction labor. On admission, the patient reported failure epidural anesthesia during previous delivery. An catheter was placed, only at high doses local anesthetic. patient’s maximum pain level never reached score 2 out 10. Conclusion: most common causes regional technical or placement failure, related itself, localized infection. This appeared have true resistance, which overcome doubling customary concentration Atypical responses anesthetics observed in may be due incomplete penetrance mutations sodium channels since work through blocking nerve conduction acting on these channels.